COMPOSITION:

Pimobendan - 5 mg

INDICATIONS:

Opulence H+ (Pimobendan) is indicated for the management of the signs of mild, moderate or severe (modified NYHA Class IIa, IIIb or IVc) congestive heart failure in dogs due to atrioventricular valvular insufficiency (AVVI) or dilated cardiomyopathy (DCM).

Opulence H+ is indicated for use with concurrent therapy for congestive heart failure (e.g. furosemide, etc.) as appropriate on a case-by-case basis.

• A dog with modified New York Heart Association (NYHA) Class II heart failure has fatigue, shortness of breath, coughing, etc. apparent when ordinary exercise is exceeded.
• A dog with modified NYHA Class III heart failure is comfortable at rest, but exercise capacity is minimal.
• A dog with modified NYHA Class IV heart failure has no capacity for exercise and disabling clinical signs are present even at rest.

DOSAGE AND ADMINISTRATION:

Opulence H+ should be administered orally at a total daily dose of 0.23 mg/lb (0.5 mg/kg) body weight, using a suitable combination of whole or half tablet. The total daily dose should be divided into 2 portions that are not necessarily equal and the portions should be administered approximately 12 hours apart (i.e., morning and evening).

The tablets are scored and the calculated dosage should be provided to the nearest half-tablet increment.

WARNINGS:

Only for use in dogs with clinical evidence of heart failure.

At 3 and 5 times the recommended dosage, administered over a 6-month period of time, Pimobendan caused an exaggerated hemodynamic response in the normal dog heart, which was associated with cardiac pathology.

HUMAN WARNINGS:

Not for use in humans. Keep this medication out of reach of children. Consult a physician in case of accidental ingestion by humans.

PRECAUTIONS:

The safety of Opulence H+ has not been established in dogs with asymptomatic heart disease or in heart failure caused by aetiologies other than AVVI or DCM.

The safe use of Opulence H+ has not been evaluated in dogs younger than 6 months of age, dogs with congenital heart defects, dogs with diabetes mellitus or other serious metabolic diseases, dogs used for breeding, or pregnant or lactating bitches.

PRESENTATION: Box of 30 tablets